Students from Uxbridge College triumphed in a competition to design a new soft drink.
Teams in the contest on 13 and 14 November had to invent and decide how to market a new special-edition drink tied in with the 2012 Olympics, then present their idea to a panel of judges in the style of the BBC programme Dragon's Den.
Uxbridge College's team from The Academy won the Year 12/13 category with their grape and apple drink, Grapple.
Guru Nanak School, Rosedale College, Harlington Community School, and Mellow Lane School, all in Hayes, and Stockley Academy in Yiewsley also took part in the event, part of Enterprise Week.
Each team had to operate as a company with members taking on roles such as CEO (Chief Executive Officer) or New Product Development Manager.
Prizes were presented by middle-distance runner Mo Farah, the second fastest Briton ever at 5000m and an Olympic hopeful.
Members of the winning teams were each presented with an iPod shuffle music player and £20 shopping vouchers.
The competition, which was sponsored by Coca-Cola and Hillingdon Community Trust and run with Hillingdon Education Business Partnership and Hillingdon Business Forum, was held at the BA Concorde Club in Heston, Hounslow.
Laraine Smith, Principal of Uxbridge College, said: "We are delighted to be the winners of this competition testing entrepreneurial and team skills, especially when up against such tough competition as the Guru Nanak team, who came second. The Coca-Cola Challenge has proved a great opportunity for students from The Academy at Uxbridge College, which teaches A-levels and GCSEs, to show that they can compete and survive in the real world as well as achieving in their academic studies."